Chemical Sciences

The Centre for Rapid Online Analysis of Reactions (ROAR) provides clients with the hardware, software and expertise needed to support data-rich experimentation in synthetic chemistry. It aims to pave the way for Synthesis 4.0, develop the next generation of (automated) synthesis and analytical technologies – and help the UK take the lead in Molecular Sciences.

The Centre supports fundamental and translational research with the protocols and tools required for rapid execution and analysis of reactions – and provides solutions to optimise reaction efficiency, selectivity, and robustness.

ROAR also works with vendors to develop the next generation of technologies in chemical synthesis, reaction analysis, laboratory automation and optimisation.

Training in chemical synthesis, analytical science, automation/robotics, reaction engineering and mathematical/data analysis can also be provided to future-proof your work-force.

Capabilities of the Centre include…

 

Robotic reactor platforms for high-throughput parallel experimentation

  • Handles plates, vials and bottles up to 125 mL
  • Automated dispensing of solids and liquids
  • Automated sampling during reactions
  • High temperature and pressure capabilities
  • Heated filtration for solubility and recrystallisation studies

 

Data-rich kinetic experimentation platforms for reaction progress and kinetic analysis across scales from 2 mL to 1 L.

  • Calorimetry
  • In-situ infra-red spectroscopy
  • UV-vis spectroscopy
  • Automated sampling
  • Collects temperature, pH and other PAT data

 

Continuous flow reactors for investigative research and scale up.

  • Homogeneous and multiphase systems
  • High temperature (< 450 °C) and pressure (< 200 bar)
  • Photochemistry
  • In-line IR spectroscopy

 

Analytical instrumentation dedicated for rapid orthogonal analysis of reactions.

  • uPLC-MS with rapid sampling capability
  • SFC and uPLC hybrid system for rapid chiral analysis
  • Further analytical capabilities available within the Department of Chemistry Measurement Suite

 

Partners also provide additional capabilities and resources.

 

Our consultants are world-leading experts in their field, committed to on-going research.

Related Insights

Life after lockdown: Transport

Life after lockdown: Transport

COVID-19 has changed everything. Or has it? How can transport companies, commuters and consumers adjust? Planes, trains and automobiles - best practice, e-mobility and air quality discussed. read more

Design Psychology

Design Psychology

As human-facing technologies change the way we interact, Dr Nejra van Zalk considers how mental health can be put at the forefront of digital platform design. read more

Factories of the Future

Factories of the Future

Additive manufacturing is an automated production process enabling complex 3D designs to be transformed into physical objects. Read about the benefits and implications. read more

Related case studies

Putting science into Sci-Fi

Putting science into Sci-Fi

When Left Bank Pictures (producers of The Crown and Lost) were looking for someone to give their Sci fi adventure, ORIGIN, a touch of realism - they called upon Imperial Consultants. Thanks to his previous work with filmmakers, writers and artists, they were introduced to Dr Roberto Trotta, a theoretical cosmologist renowned for taking on the unusual - and gifted in translating ‘science-speak’ into layman’s terms. read more

Bio-Inspired Aerial Robotics

Bio-Inspired Aerial Robotics

Dr Mirko Kovac is Director of the Aerial Robotics Laboratory at Imperial College London, and Senior Lecturer in Aero-structures. His research focuses on the development of biologically inspired flying robots for distributed sensing of air and water, search and rescue plus autonomous repair and construction. read more

Structures under extreme loading

Structures under extreme loading

The consultants shared their expertise in seismic assessment and design to support the development of EN1998, also known as Eurocode 8. read more

Latest news

Robotic testing platform helps to scale up COVID-19 testing capacity

Robotic testing platform helps to scale up COVID-19 testing capacity

Imperial team has repurposed robotic technology normally used for synthetic biology research to help with testing for COVID-19. read more

FREE Fetal Heart webinar – ON DEMAND

FREE Fetal Heart webinar – ON DEMAND

Catch up on the third in our series of four, educational webinars exploring Fetal Medicine. In this event we will explore cases where fetal cardiology, fetal medicine, clinical genetics and obstetric management are integrated in one patient pathway. Delivered by Imperial’s Professor Christoph Lees, and supported by GE HealthCare. read more

Webinar: Imaging in the Management of Preterm Birth. 12 noon (UK) June 24

Webinar: Imaging in the Management of Preterm Birth. 12 noon (UK) June 24

Book your place for the second in the “East meets West” Obstetrics and Gynaecology Ultrasound Webinar Series 2021 - supported by Samsung. For general obstetricians, those who specialise in the prevention and management of preterm birth plus sonologists, sonographers and fetal medicine specialists. read more