Chemical Sciences

The Centre for Rapid Online Analysis of Reactions (ROAR) provides clients with the hardware, software and expertise needed to support data-rich experimentation in synthetic chemistry. It aims to pave the way for Synthesis 4.0, develop the next generation of (automated) synthesis and analytical technologies – and help the UK take the lead in Molecular Sciences.

The Centre supports fundamental and translational research with the protocols and tools required for rapid execution and analysis of reactions – and provides solutions to optimise reaction efficiency, selectivity, and robustness.

ROAR also works with vendors to develop the next generation of technologies in chemical synthesis, reaction analysis, laboratory automation and optimisation.

Training in chemical synthesis, analytical science, automation/robotics, reaction engineering and mathematical/data analysis can also be provided to future-proof your work-force.

Capabilities of the Centre include…

 

Robotic reactor platforms for high-throughput parallel experimentation

  • Handles plates, vials and bottles up to 125 mL
  • Automated dispensing of solids and liquids
  • Automated sampling during reactions
  • High temperature and pressure capabilities
  • Heated filtration for solubility and recrystallisation studies

 

Data-rich kinetic experimentation platforms for reaction progress and kinetic analysis across scales from 2 mL to 1 L.

  • Calorimetry
  • In-situ infra-red spectroscopy
  • UV-vis spectroscopy
  • Automated sampling
  • Collects temperature, pH and other PAT data

 

Continuous flow reactors for investigative research and scale up.

  • Homogeneous and multiphase systems
  • High temperature (< 450 °C) and pressure (< 200 bar)
  • Photochemistry
  • In-line IR spectroscopy

 

Analytical instrumentation dedicated for rapid orthogonal analysis of reactions.

  • uPLC-MS with rapid sampling capability
  • SFC and uPLC hybrid system for rapid chiral analysis
  • Further analytical capabilities available within the Department of Chemistry Measurement Suite

 

Partners also provide additional capabilities and resources.

 

Our consultants are world-leading experts in their field, committed to on-going research.

Related Insights

Innovative body modifications

Innovative body modifications

From mind reading machines to edible water bottles, self-learning bionic hands to smart tattoos, the feature article highlights a range of inventions created by staff, students and citizen scientists which aim to make our lives a little more exciting and a little easier. read more

Mission to the Sun

Mission to the Sun

Understanding the Sun’s moods, and how these influence the solar wind, is the aim of Solar Orbiter, a European Space Agency mission that has Imperial-built kit on board. read more

The future of urban air

The future of urban air

How could future technologies and social interventions change urban air for city dwellers? Hover over the map created by Imperial's researchers, futurists and our Tech Foresight team. read more

Related case studies

Putting science into Sci-Fi

Putting science into Sci-Fi

When Left Bank Pictures (producers of The Crown and Lost) were looking for someone to give their Sci fi adventure, ORIGIN, a touch of realism - they called upon Imperial Consultants. Thanks to his previous work with filmmakers, writers and artists, they were introduced to Dr Roberto Trotta, a theoretical cosmologist renowned for taking on the unusual - and gifted in translating ‘science-speak’ into layman’s terms. read more

Hepatitis C genotype and drug resistance testing

Hepatitis C genotype and drug resistance testing

Genotype and resistance testing for new direct-acting antiviral (DAA) drugs designed to treat Hepatitis C virus (HCV). read more

Bio-Inspired Aerial Robotics

Bio-Inspired Aerial Robotics

Dr Mirko Kovac is Director of the Aerial Robotics Laboratory at Imperial College London, and Senior Lecturer in Aero-structures. His research focuses on the development of biologically inspired flying robots for distributed sensing of air and water, search and rescue plus autonomous repair and construction. read more

Latest news

Webinar: Imaging in the Management of Preterm Birth. 12 noon (UK) June 24

Webinar: Imaging in the Management of Preterm Birth. 12 noon (UK) June 24

Book your place for the second in the “East meets West” Obstetrics and Gynaecology Ultrasound Webinar Series 2021 - supported by Samsung. For general obstetricians, those who specialise in the prevention and management of preterm birth plus sonologists, sonographers and fetal medicine specialists. read more

International Women’s day

International Women’s day

Monday March 8th celebrates the social, economic, cultural and political achievements of women, globally and this year's theme reminds us to challenge and call out gender bias and inequality. We've asked some Imperial role models how they #ChoosetoChallenge. read more

Tackling London’s air pollution will increase life expectancy of children

Tackling London’s air pollution will increase life expectancy of children

Report by researchers from Environmental Research Group predicts London air quality policies, and wider improvements in air quality, will increase average life expectancy of a child born in London in 2013 by six months. read more